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VIP5 | VIP | 5mg10瓶 | >99% 純度

包括導入的目錄回饋;未經驗證的 Pepverlabs 購買。

5 mg × 10 瓶 · ≥ 99.0% 純度

產品名稱
VIP (血管活性腸肽)
CAS 號
37221-79-7
分子式
C₁₄₇H₂₃₇N₄₃O₄₃S
純度(HPLC)
≥ 99.0%
分子量
3326.82 Da
pH值
4.0–6.0,无菌冻干粉末,含醋酸盐缓冲液
外觀
白色凍乾粉末
儲存
儲存於 2°C 至 8°C(冷藏)/-20°C(長期)
可選規格

Selected: 5 mg × 10 vials

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僅供實驗室研究使用。不適用於人體或獸用。

SKU: PVL-VIP研究肽
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VIP5 / 研究資料

VIP · 研究資料

對材料、其研究背景和分析要求的清晰檢視。

基本介紹

血管活性腸肽 (VIP) 是一種在神經、胃腸和其他組織中發現的神經內分泌訊號肽。此列表提供了一種合成研究材料,用於研究受體訊號傳導、細胞反應和實驗室模型中的肽處理。

VIP 研究跨越多個生物系統,因此實驗結果取決於受體亞型、細胞型別和測量的終點。血管反應、炎症標誌物和神經訊號反應應視為獨立觀察,而不是可互換的活性測量。

研究亮點

VPAC 受體訊號傳導

VIP 與 VPAC 家族受體相互作用。

免疫細胞分化

VIP 已在來源於人單核細胞的樹突狀細胞中進行研究。

血管模型差異

VIP 反應在血管區室之間有所不同。

上皮屏障通路

屏障效應取決於組織和實驗挑戰。

神經元 cAMP/PKA 反應

活細胞測量提供了神經訊號的時間分辨檢視。

胰腺和代謝研究

孤立的小鼠胰島實驗研究了 VIP 暴露後的胰島素釋放、鈣攝取和電活動。

作用機制 · 研究背景

  1. VPAC 受體訊號傳導

    VIP 與 VPAC 家族受體相互作用。這些 G 蛋白偶聯受體可以刺激腺苷酸醯化酶並增加細胞內環磷酸腺苷。受體選擇性對照有助於區分 VIP 反應與相關肽如 PACAP 的反應。

  2. cAMP 和下游反應

    訊號幅度和時序取決於實驗模型。大鼠皮層組織中的活細胞研究測量了 VIP 和相關配體的不同 cAMP/PKA 反應;單一終點測量可能會錯過這些差異。

  3. 血管模型差異

    VIP 反應在血管區室之間有所不同。在豬基底動脈的研究中,將受體定位與舒張反應聯絡起來,說明了物種、組織準備和內皮完整性為何應記錄在實驗記錄中。

  4. 免疫細胞分化

    VIP 已在來源於人單核細胞的樹突狀細胞中進行研究。一項主要研究報告了一種產生 IL-10 的耐受性群體,能夠支援調節性 T 細胞反應。這是一個明確的細胞培養髮現,而不是逆轉系統性自身免疫疾病的證據。

  5. 上皮屏障通路

    屏障效應取決於組織和實驗挑戰。在感染模型中的研究考察了緊密連線定位和 MLCK 相關訊號傳導;其他腸道準備顯示出不同的通透性反應。這些發現不支援 VIP 總是減少屏障洩漏的普遍主張。

擴充套件研究考慮

  1. 神經元 cAMP/PKA 反應

    活細胞測量提供了神經訊號的時間分辨檢視。大鼠皮層研究比較了 VIP 與相關神經肽,並顯示了為何受體身份、反應幅度和恢復時間應單獨記錄。

  2. 胰腺和代謝研究

    孤立的小鼠胰島實驗研究了 VIP 暴露後的胰島素釋放、鈣攝取和電活動。一個單獨的轉基因模型共同表達了 VIP 和 PHM-27,因此其代謝發現不能僅歸因於單獨的 VIP 瓶。

  3. 炎症和上皮終點

    細胞因子輸出、調節細胞表型和屏障通透性是不同的結果。結合這些測量可以澄清模型,而一個終點的變化並不能確立完全的免疫恢復或臨床治療效果。

瓶內成分

產品名稱
VIP (血管活性腸肽)
純度(HPLC)
≥ 99.0%
外觀
白色凍乾粉末
可選規格
5 mg × 10 瓶;10 ml × 10 瓶

研究應用

  • 受體測定
  • 神經內分泌訊號傳導

僅供實驗室研究的課題方向;不暗示任何臨床效果。

相容性與相關資源

請確認實際物料的溶劑與檢測相容性。相關列表僅為目錄參考,並非經過驗證的混合配方。

材料和包裝

列出的外觀:白色凍乾粉末。

可用試劑盒規格:5 mg × 10 瓶;10 ml × 10 瓶。選擇上面的選項以檢視其當前價格和可用性。

儲存和處理

來源列出的儲存條件:在 2°C 到 8°C(冷藏)/-20°C(長期)下儲存。遵循實際批次提供的處理說明和您實驗室的程式。

分析檔案

參考分析檔案可與此列表一起提供。檢查材料身份、批號和測試日期與所提供的批次是否一致;如需當前批次文件,請聯絡我們。

科學參考文獻

這些出版物描述了研究的分子和實驗模型。它們不認證特定提供批次的身份、質量或效果。

Pepverlabs · 參考資料

來自原始商品頁的反饋

10 個第三方條目的簡要編輯摘要。這些不是經過驗證的 Pepverlabs 購買;完整的文字可在原始列表中找到。 檢視原始來源 ↗

附加資訊

規格

5 mg × 10 vials, 10 ml × 10 vials

研究規格

產品名稱VIP (血管活性腸肽)
CAS 號37221-79-7
分子式C₁₄₇H₂₃₇N₄₃O₄₃S
純度(HPLC)≥ 99.0%
分子量3326.82 Da
pH值4.0–6.0,无菌冻干粉末,含醋酸盐缓冲液
外觀白色凍乾粉末
儲存儲存於 2°C 至 8°C(冷藏)/-20°C(長期)

分析檔案

PEPVERLABS / 回饋

客戶評價

評論以原始語言顯示。

4.97 / 5★★★★★30 條評價

包括導入的目錄回饋。導入的條目未經驗證的 Pepverlabs 購買。

5 ★29
4 ★1
3 ★0
2 ★0
1 ★0
Source reviewer

1

尼婭姆·P。

This 10-vial bulk pack has a great limited-time sale discount that cuts my monthly lab raw material costs noticeably. Vial-to-vial powder texture, concentration and purity show zero variance, making intestinal and vascular signaling experimental data highly repeatable across test batches. 8

奧林·Q。

Two volume specifications (5mg and 10mg per vial) fit all my research scales perfectly. The 5mg vial is ideal for small preliminary screening trials; I only reconstitute one vial per experiment to avoid wasting diluted VIP that quickly loses biological activity once mixed with solvent.

林登·N。

The balanced acetate buffer blend drastically cuts down peptide residue stuck to inner vial glass after mixing. I recover nearly 100% of the labeled 5mg lyophilized powder each time, eliminating major dosing errors in quantitative vasoactive receptor binding research.

Hesper S.

This 10-vial bulk pack includes a limited-time promotional markdown that significantly cuts my monthly lab raw material overhead. Vial-to-vial powder texture, concentration and purity show zero measurable deviation, making all my intestinal signaling experimental data highly repeatable batch after batch.

梅里克·O。

UV light speeds up VIP peptide oxidation drastically, so I store all sealed vials inside opaque refrigeration storage boxes. Unopened stock stays pure white without yellowing after over a month of cold storage, and reconstituted VIP liquid remains transparent without precipitates for several refrigerated days.

金斯利·M。

Consistent ≥99% HPLC purity, clear dual-temperature storage guidelines, flexible 5mg/10mg vial options and stable cross-batch quality make this VIP5 my exclusive VIP peptide supply. Quality never shifts between restock shipments for my long-term gastrointestinal and circulatory pathway research projects.

Darien K.

VIP is my core research compound for gastrointestinal function, vasodilation and immune regulation pathway studies. The built-in acetate buffer holds pH steady between 4.0–6.0 to slow peptide denaturation post-reconstitution, and mixed working solution stays transparent for multiple refrigerated testing days. All glass vials arrived fully intact with zero breakage during cross-border international lab shipping.

昆廷·S。

The CAS number, molecular formula and 3326.82 Da molecular weight fully match official biochemical reference data. No bulking fillers or degraded peptide fragments are detected via HPLC testing, and strict cold storage protocols avoid irreversible folding damage to the large VIP protein structure.

Jasper W.

The optimized balanced acetate buffer blend drastically minimizes peptide adhesion to vial glass walls post-dissolution. I recover nearly 100% of the labeled 5mg lyophilized powder from every vial, removing major dosing inaccuracies in quantitative VIP receptor binding and gastrointestinal tissue regulation research.

Marlow P.

This VIP vasoactive intestinal peptide is sterile white acetate-buffered lyophilized powder with HPLC purity above 99%. Short-term storage requires refrigeration at 2–8°C, while long-term preservation needs -20°C dark freezer storage. Proper temperature control keeps the long peptide chain intact without hydrolysis or fragmentation over months.

瑞斯·Q

Consistent certified ≥99% HPLC purity, dual flexible storage temperature guidelines, two convenient vial dosage sizes and rock-solid cross-batch uniformity make VIP5 my permanent exclusive VIP peptide supplier. I place monthly recurring bulk restock orders for my long-term gastrointestinal, circulatory and immune regulatory lab research projects, with zero fluctuation in powder solubility or biological activity between every shipment.

西拉斯·U。

Every vial in the 5mg×10 bulk kit holds ultra-fine uniform white lyophilized powder that dissolves completely into clear particle-free liquid. The hermetic gold crimp stopper locks out external humidity, so the powder never clumps even after repeated syringe punctures to draw partial samples for vascular pathway testing.

塔莉·V。

This VIP vasoactive intestinal peptide is sterile white acetate buffered lyophilized powder with HPLC purity above 99%. Short-term storage needs consistent 2–8°C refrigeration, while long-term stock must be sealed and stored at -20°C away from light. Following this two-stage storage rule fully prevents the long polypeptide chain from hydrolysis and fragmentation for months.

Fiora M.

I ran side-by-side comparative gastrointestinal cell trials with VIP sourced from 7 different suppliers, and this acetate lyophilized VIP5 variant delivers unmatched solubility with barely any powder residue sticking to inner vial glass. Slow gentle circular swirling achieves full dissolution; harsh vigorous shaking fractures the peptide backbone and invalidates vasodilatory assay readouts.

Peregrine V.

I completed blinded parallel biological activity testing between this VIP5 and two competing supplier batches. This product delivers the most consistent vasodilatory cellular response across all test tissue groups, thanks to its ultra-high ≥99% HPLC purity with negligible trace impurities that do not interfere with assay signal detection.

瑞亞·T。

VIP peptide is my core research material for gastrointestinal and vasodilation mechanism studies. The built-in acetate buffer locks pH within 4.0–6.0, greatly slowing protein denaturation after reconstitution. All glass vials arrived fully intact without cracks or leakage during international lab shipping.

Oriana K.

Advanced industrial lyophilization technology creates ultra-fine free-flowing white powder with zero hard compacted chunks settled at the vial bottom. When I only require tiny micro-dose samples for early-stage preliminary screening assays, I can extract partial dry powder without fully reconstituting the entire vial to conserve expensive VIP stock.

Ilaria T.

UV light is the primary trigger for VIP molecular breakdown, so I store all unopened sealed vials inside fully opaque fridge and freezer storage bins. After three full months of unbroken -20°C frozen storage, the powder remains bright pure white with no yellowing, and reconstituted peptide liquid never develops cloudiness or solid precipitates over multi-day testing cycles.

Nevin Q.

Every vial inside the 10-vial bulk pack holds uniform fine white lyophilized powder that dissolves fully into particle-free clear liquid. The airtight gold crimp cap blocks moisture well, so powder never clumps even after repeated punctures to draw small aliquots for physiological research tests.

Kaelin Y.

A lab trainee accidentally left an unopened VIP vial out at room temperature for 3 full days. Upon follow-up testing, the powder compacted into hard clumps and displayed drastically weakened vasodilatory activity, highlighting how strict cool, light-free storage is mandatory for this peptide.

佩斯利·R。

I’ve sourced VIP peptides from multiple suppliers for comparative cell culture trials, and this acetate lyophilized variant delivers superior solubility with minimal glass-wall adhesion. Slow gentle swirling achieves full dissolution; rough shaking will split the peptide chain and invalidate assay readouts.

Gareth P

Two flexible dosage specifications (5mg,10mg per vial) perfectly fit all stages of my research workflow. The standard 5mg single vial fill size is calibrated for small preliminary intestinal screening experiments; I only reconstitute a single vial per testing cycle to eliminate waste of costly diluted VIP that rapidly loses biological potency once mixed with solvent.

Maren F.

International bulk shipping packaging uses custom individual shock-absorbent foam dividers to isolate each glass vial and prevent collision damage during transit. I’ve placed four separate overseas bulk orders to date, and zero vials arrived cracked, chipped, leaking or contaminated upon delivery to my research facility.

Celandine W.

Each vial inside the 5mg×10 bulk kit holds ultra-fine uniform white lyophilized powder that dissolves instantly into particle-free clear aqueous liquid. The airtight gold aluminum crimp cap creates a full humidity barrier, so powder never clumps even after repeated syringe punctures to draw tiny partial aliquots for intestinal epithelial cell testing.

Elowen R.

The official CAS registry number, molecular formula and 3326.82 Da molecular weight align perfectly with peer-reviewed biochemical reference datasheets. This lab-grade VIP contains zero inert bulking fillers or fragmented peptide sequences, and consistent cool/dark storage blocks photo-oxidation that degrades its vasoactive peptide structure.

Niven D.

This VIP peptide extends far beyond basic gastrointestinal research. I also utilize it for pulmonary vasoregulation and immune cell culture trials, and its stable 4.0–6.0 pH range removes the need to add extra neutralizing buffer additives to my cell culture media mixtures.

Linden C.

I perform random blind HPLC spot quality checks on randomly selected vials from every shipment batch, and every single sample consistently meets the advertised ≥99% purity threshold with no unknown impurity peaks on chromatogram outputs. Complete batch purity certification is included with every order, fully compliant for university lab audit and research paper documentation standards.

Querida F.

The dual storage options are incredibly convenient for my lab workflow. Vials I plan to use within one month stay in the 2–8°C lab fridge, while unopened reserve stock goes into -20°C long-term freezer storage, with no measurable loss of peptide activity across either storage method when light exposure is controlled.

Briar H.

This VIP5 Vasoactive Intestinal Peptide is sterile acetate-buffered white lyophilized powder with HPLC purity ≥99%. Short-term lab storage works at 2–8°C refrigeration, while long-term preservation requires sealed vials kept at -20°C with full light & moisture shielding. Temperature-controlled storage stabilizes its long amino acid chain, avoiding hydrolysis and loss of vasoregulatory activity for gastrointestinal and circulatory signaling research.

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