Description
Basic introduction
MOTS-c is a 16-amino-acid peptide described in research on mitochondrial-derived signaling. Its sequence is associated with the mitochondrial 12S rRNA region, and early investigations examined cellular metabolism and mouse metabolic models.
A mitochondrial origin does not mean that every experimental effect occurs inside mitochondria. The research connects a defined peptide to broader metabolic measurements that depend on the biological model and study conditions.
Mechanism of action · Research context
Mitochondrial-derived sequence
MOTS-c is studied as a mitochondrial-derived peptide. Sequence confirmation provides the starting point for comparison with the material used in published experiments.
Metabolic pathway changes
Early studies examined folate and purine-related metabolism. These observations linked peptide exposure to changes in cellular metabolic pathways rather than establishing a single direct receptor mechanism.
AMPK-associated responses
AMPK-related signaling featured in the original research. Such signaling measurements should be considered alongside the measured metabolic phenotype rather than treated as a complete explanation of every effect.
Extended research considerations
Cellular metabolic assays
Specify whether the endpoint concerns metabolites, signaling or energy use. Different assay types capture different stages of the response and may not change in parallel.
Animal-model context
The original work included mouse metabolic experiments. Results from those models should remain distinct from claims about human exercise performance or weight management.
Comparative material quality
Compare the actual peptide sequence, content and analytical profile. Shared mitochondrial-research terminology does not make MOTS-c interchangeable with SS-31 or a cofactor such as NAD+.
Material and packaging
Listed appearance: White Lyophilized Powder.
Available kit specifications: 10 mg × 10 vials; 20 mg × 10 vials; 40 mg × 10 vials. Select an option above to view its current price and availability.
Storage and handling
Source-listed storage condition: Store at -20°C (Protect from light and moisture). Follow the handling instructions supplied with the actual batch and your laboratory's procedures.
Analytical documentation
Reference analytical documents are available with this listing. Check the material identity, batch number and test date against the batch supplied; contact us for current batch documentation.
Scientific references
These publications describe the studied molecules and experimental models. They do not certify the identity, quality or effects of a particular supplied batch.
- Original MOTS-c metabolic research (Cell Metabolism, 2015)
View report
View report
Ewan Maeve –
The lyophilized white powder stays loose and free-flowing, never compacting into hard sediment on the bottle base. For quick preliminary metabolic screening assays, I take small dry powder samples with sterile spatulas instead of mixing the entire vial, cutting lab MOTS-C waste by almost half.
Wesley Rainer –
Consistent certified ≥99% HPLC purity, clear strict low-temperature dark dry storage guidelines, fixed standardized 10mg vial dosage and rock-solid cross-batch uniformity make MS10 my exclusive Human MOTS-C peptide supplier. I place monthly recurring bulk restock orders for my long-term mitochondrial function, insulin regulation and anti-aging metabolic lab research projects, with zero fluctuation in powder solubility or biological activity between every shipment.
Blair Rowe –
I stored sealed MS10 vials in dark constant -20°C freezer cabinets for two full months, white powder showed zero yellowing or clumping. When reconstituted for follow-up cell tests, its fat-burning and energy-balancing effect matched fresh new stock fully. My old MOTS-C brand degraded and turned pale yellow after only three weeks frozen.
Willis Pruitt –
Consistent certified ≥99% HPLC purity, clear strict low-temperature dark dry storage guidelines, three flexible vial dosage sizes and outstanding cross-batch uniformity make MS10 my exclusive supplier for Human MOTS-C peptide. I place monthly recurring bulk restock orders for my long-term mitochondrial function, insulin regulation and anti-aging metabolic research projects, with zero fluctuation in powder solubility or biological activity between every shipment.
Marnie Colton –
Every vial in the 10mg×10 bulk kit holds free-flowing ultra-fine white lyophilized powder that dissolves completely into clear particle-free liquid after slow gentle swirling. The airtight blue aluminum flip cap fully blocks external moisture, so powder never clumps even after repeated needle punctures to draw tiny partial aliquots for adipocyte mitochondrial cell culture testing.